• August 24, 1910: Thomas B. Enders, M.D., a Yale-educated graduate of the College of Physicians and Surgeons (Columbia) and Hartford surgeon purchases Enders Island from the Daughters of Charity of St. Vincent DePaul, and work begins almost immediately developing Enders Island.
• 1918: The construction of the Enders House begins.
• March 1, 1920: Dr. Enders purchases a right of way from the Mason's Island Company and proceeds to build a bridge connecting Enders Island to Mason's Island.
• December 22, 1925: Dr. Enders marries Alys VanGilder in the West End Presbyterian Church, in New York City.
• Work continues on Enders Island, including the extensive stone tiles designed by Mrs. Enders and featured throughout the arts and crafts style mansion.
• January 16, 1932: Dr. Enders conveys Enders Island to Mrs. Enders.• January 26, 1943: Dr. Enders dies at the age of 77. He leaves the sum of $100,000 (nearly $1.5 million in current dollars) to Mrs. Enders “for work, labor, and materials, in the repair, restoration, or improvement of the land and buildings known as Enders Island.”